Chemicals are part and parcel of many productions and cannot be avoided. Due to the effects of chemicals (Toxicity, corrosiveness and non-corrosiveness), this course has been developed to offer knowledge and skills to students to be able to identify the hazardous chemical, address a preventive measure, understand the Material Safety Data Sheets and Container labels etc. This course introduces students to ways of informing staff, visitors etc. on the hazards present at a given location, the type of PPE required, the type of training required, type of supervision, escape routes and so on.
Learning Outcome:
· Ability to understand industrial chemicals and their effects
· Ability to use and explain Material Safety Data Sheets [MSDS]
· Ability to prevent poisoning from chemicals and use of appropriate PPE
Duration:
2 weeks
Teaching Methods:
Modified lecture, individual & group assignments and presentations, videos, case studies and Problem based learning.
Assessment:
Continuous assignments/practicals [40%], and final examination [60%].
Course Content:
· Introduction to Industrial Toxicology
· Toxic substances: risks involved, handling, storing, labeling, precautionary measures.
· Principles of Industrial Toxicology – Routes of entry and target organs. Dosage-response relationships. Toxicity Indices.
· Health Effects; Acute (Short-term exposure) & Chronic (Long-term exposure).
· Storage of Toxicants in tissues (Liver & kidney) and Routes of Excretion.
· Classification of Toxic materials and Chemical Hazards in the working environment
· Supply chain, hazard communication and training; Material Safety Data Sheets, Container labeling, Roles of the Manufacturer, Importer/supplier, Employer and Employees
· Assessment of risks associated with the use of Hazardous substances Control of substances hazardous tohealth
Study Material:
1. Alhoshani A. Pharm B. 2012. Excretion of Drugs
2. Autumn AA. Directions. 2016. UN Classification of Chemical Hazards
3. Bahadori, A. 2017. Hazardous Area Classification in Petroleum and Chemical Plants: A Guide to Mitigating Risk
4. Boss, M.J. 2017. Handbook of Chemical Regulations: Benchmarking, Implementation, and Engineering Concepts
5. Duffus, J.H. & Worth, H.G.J. 2015. Fundamental Toxicology
6. Kane, A.S. 2014. Principles of Toxicology
7. Kar, B. & Cochran, D.M. 2020. Risk Communication and Community Resilience.
8. Klaassen, C. & Watkins, J. 2015. Casarett & Doull's Essentials of Toxicology
9. Kolok, A. 2016. Modern Poisons: A Brief Introduction to Contemporary Toxicology
10. McGuire M. M.2016. The Hazard Communication Answer Book
11. OSHA 3844-02. 2016. Hazard Communication, Hazard Classification Guidance for Manufacturers, Importers, and Employers.
12. Phillip L. W. 2011. Principles of Toxicology, Environmental and Industrial Applications.
13. Richardson. 2012. Chemical and Hazardous Materials Safety
14. Safety Institute of Australia Ltd. 2012. Chemical Hazards Core body of knowledge for the generalists of OHS professional
15. Stine, S.K. & Brown, T.M. 2015. Principles of Toxicology
16. Urben, P. 2017. Bretherick's Handbook of Reactive Chemical Hazards
17. US-OSH. 2014. Hazard Communication: Small Entity Compliance Guide for Employers That Use Hazardous Chemicals
18. Winder, C. 2019. Occupational Toxicology
- Lecturer: Joseph Onyango